When corporate power goes unchecked, integrity becomes its first casualty. Trust Betrayed examines a striking case of CEO misconduct—how authority, when left unchallenged, enabled fraud and manipulation at the highest level of leadership. The article explores the warning signs that were overlooked, the culture that allowed deception to thrive, and the lessons organizations must learn to prevent history from repeating itself.

Switzerland’s revised Cartel Act is more than a legislative update - it’s a strategic shift in how companies must approach antitrust risk. In this edition, I break down what’s changed, why it matters for regulated industries like Life Sciences, and how compliance leaders can turn enforcement pressure into a competitive advantage.

In our March edition, we explored the complexities of pharmaceutical donations to NGOs, highlighting the tensions between goodwill, compliance, and the demand for transparency. This month, we move the conversation forward.

This edition reflects on the priorities that have shaped CEO agendas over the past year and contrasts them with the rapidly evolving geopolitical and regulatory environment defining today’s business landscape. As global uncertainty intensifies—from supply chain disruptions and sanctions to heightened scrutiny around ethics, sustainability, and data governance—leaders are being tested on their ability to align bold strategic intent with the realities of compliance and accountability. The balance between growth and governance has never been more critical. This issue explores how organizations are adapting their strategies to maintain agility, integrity, and resilience in a world where regulatory expectations increasingly define competitive advantage.

The EU Clinical Trial Regulation (CTR) (Regulation (EU) No 536/2014) modernizes the oversight of clinical research across Europe by harmonizing trial approvals and enhancing transparency through the Clinical Trials Information System (CTIS). It replaces the former directive with a unified framework that strengthens patient safety, data integrity, and ethical standards while streamlining cross-border collaboration and regulatory efficiency.